Publications

Publications

Lung Cancer

  1. Faruki H, Mayhew GM, Serody JS, Hayes DN, Perou CM, Lai-Goldman M.  Lung Adenocarcinoma and Squamous Cell Carcinoma Gene Expression Subtypes Demonstrate Significant Differences in Tumor Immune Landscape.  Jrnl Thoracic Oncology.  2017 Mar 21. pii: S1556-0864(17)30214-9. doi: 10.1016/j.jtho.2017.03.010. Link
  2. Faruki H, Mayhew G, Feng C, Wilkerson M, Horten B, et al.   Validation of the Lung Subtyping Panel in Multiple Fresh-Frozen and Formalin-Fixed Paraffin Embedded Lung Tumor Gene Expression Data sets.  (2016) Archives Pathol Lab Medicine. 140(6): 536-542. Link
  3. Faruki H, Mayhew G, Hayes N, Serody J, Perou C., Lai-Goldman M.  Immune Cell Activation among Lung Adenocarcinoma and Squamous Cell Carcinoma Subtypes and CD274(PD-L1) Expression.  Presented at the Annual Association of Clinical Oncology Meeting.  Abstract #3077.  June 3-7, 2016 Chicago, IL. Link
  4. Mayhew G, Hayes N, Perou C, Lai-Goldman M, Faruki H. Lung Subtyping Signature for Predicting Survival in Lung Adenocarcinoma and Relationship to Other Gene Expression Prognostic Panels.  Abstract #ST49.  Presented at the Association of Molecular Pathology Annual Meeting. Nov 5-7, 2015.  Austin, TX. Link
  5. Mayhew G, Hayes N, Perou C, Lai-Goldman M, Faruki H.  Survival Differences of Adenocarcinoma Lung Tumors with Squamous Cell Carcinoma or Neuroendocrine Profiles by Gene Expression Subtyping.  Abstract # 384.  Presented at the 16th World Conference on Lung Cancer, September 6-9, 2015; Denver. Link
  6. Zhao N, Wilkerson MD, Shah U, Yin X, Wang A, Hayward MC, Roberts P, Lee CB, Parsons AM, Thorne LB, Haithcock BE, Grilley-Olson JE, Stinchcombe TE, Funkhouser WK, Wong KK, Sharpless NE, Hayes DN. Alterations of LKB1 and KRAS and risk of brain metastasis: comprehensive characterization by mutation analysis, copy number, and gene expression in non-small-cell lung carcinoma. (2014) Lung Cancer. 86(2), 255-61. Link
  7. The Cancer Genome Atlas Research Network (TCGA). Comprehensive molecular profiling of lung adenocarcinoma. (2014) Nature. 511, 543–50. Link
  8. Wilkerson MD, Schallheim JM, Hayes DN, Roberts PJ, Bastien RRL et al. Prediction of Lung Cancer Histological Types by RT-qPCR Gene Expression in FFPE Specimens (2013) J Mol Diagn. 15(4), 485-97. Link
  9. The Cancer Genome Atlas Research Network (TCGA). Comprehensive genomic characterization of squamous cell lung cancers. (2012) Nature. 489, 519–25. Link
  10. Wilkerson MD, Yin X, Walter V, Zhao N, Cabanski CR, et al. Differential Pathogenesis of Lung Adenocarcinoma Subtypes Involving Sequence Mutations, Copy Number, Chromosomal Instability, and Methylation. (2012) PLoS ONE. 7(5):e36530. Link
  11. Grilley-Olson JE, Hayes DN, Moore DT, Leslie KO, Wilkerson MD, et al. Validation of interobserver agreement in lung cancer assessment hematoxylin-eosin diagnostic reproducibility for non-small cell lung cancer – the 2004 world health organization classification and therapeutically relevant subsets. (2013) Arch Pathol Lab Med. 136: 1-9. Link
  12. Wilkerson MD, Yin X, Hoadley KA, Liu Y, Hayward MC, et al. Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important and correspond to normal cell types. (2010) Clin Cancer Res. 16(19):4864-75. Link
  13. Shah U, Sharpless NE, Hayes DN. LKB1 and lung cancer: More than the usual suspects. (2008) Cancer Res. 68 (10), 3562-5. Link
  14. Hayes DN, Monti S, Parmigiani G, Gilks B, Naoki K, et al. Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts. (2006) J Clin Oncol. 24(31), 5079-90. Link

Head and Neck Cancer

  1. The Cancer Genome Atlas Research Network (TCGA). Comprehensive genomic characterization of head and neck squamous cell carcinomas. (2015) Nature. 517, 576-82. Link
  2. Walter V, Yin X, Wilkerson MD, Cabanski CR, Zhao N, et al. Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes. (2013) PLOS One. 8(2), e56823. Link
  3. Zhao N, Ang M-K, Yin X-Y, et al. Different cellular p16INK4a localisation may signal different survival outcomes in head and neck cancer. (2012) Br J Cancer. 107, 482–90. Link