Head & Neck

Head & Neck

Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease with multiple tumor types and varying prognosis and treatment responses. Advanced disease is associated with a 40-50 percent recurrence rate following primary treatment. Better classification tools are needed to inform therapeutic choices and improve survival.

Human papilloma virus (HPV) infection is an important risk factor, but infection is present in only a subset of cases and knowledge of HPV status alone is not sufficient to guide treatment.

We are applying our Cancer Subtyping Platform (CSP®) to develop a comprehensive picture of head and neck tumor subtypes that will guide drug development, clinical trials and patient treatment.